Syndivia In-Licenses DARx Technology for 1-to-1 Linkage of Antibodies and Payloads for Preparation of DAR1 ADC

STRASBOURG (France) – January 28, 2020 – Syndivia has acquired an exclusive license from SATT Conectus for DARx technology, which enables the generation of 1-to-1 conjugates (DAR1) using readily available protein substrates, such as therapeutic antibodies. The antibody-drug and antibody-oligonucleotide conjugates with a degree of conjugation of 1 (DAR1), produced through DARx, have demonstrated improved therapeutic indices owing to enhanced pharmacokinetics and pharmacodynamics (PK/PD) parameters.

ADC DAR1 (antibody-drug conjugation with drug-to-antibody ratio of one)

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Syndivia In-Licenses Novel Antibody Against Tumor-Specific Form of CD146 From SATT Sud-Est